Texture and Colour Enhancement Imaging in Improving Detection and Miss Rate of Premalignant Lesions

Launched by CHANGHAI HOSPITAL · Jul 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new imaging technology called Texture and Color Enhancement Imaging (TXI) to see if it can help doctors find precancerous growths in the colon more effectively than standard imaging methods. The focus is on detecting specific types of growths known as adenomas and sessile serrated adenomas, which can potentially lead to cancer if not identified and treated early.

To participate in this study, you need to be between the ages of 45 and 85 and scheduled for a screening colonoscopy, which is a test that looks for problems in the colon. You will need to give your written consent to join. However, there are certain conditions that would exclude you from participating, such as having an existing colon tumor, serious digestive issues, or if you are pregnant or breastfeeding. If you join the trial, you can expect to undergo a colonoscopy using this new imaging technology, and the trial aims to compare the effectiveness of TXI with traditional imaging methods to see which one does a better job at detecting these important lesions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients aged 45-85 years and scheduled for screening colonoscopy who provided written informed consent
• Exclusion Criteria:
• • Surveillance, diagnostic or therapeutic colonoscopy
• • Patients with an already known or suspected colorectal tumour
• • Patients with alarming symptoms and signs, including haematochezia, melena, weight loss or anaemia without specific causes, an abdominal mass and positive digital rectal examination
• • Pregnant or lactating women
• • Patients with gastrointestinal tract obstruction
• • Patients with inflammatory bowel diseases, hereditary CRC syndromes or serrated polyposis syndrome
• • Patients with abnormal blood coagulation or taking antiplatelets or anticoagulants within 7 days before colonoscopy
• • Patients with failed cecal intubation
• • Patients with poor bowel preparation quality that necessitated a second bowel preparation
• • Patients with a history of colonic resection