Effect of L-PRF on Implant Stability and Marginal Bone Levels.

Launched by DUBLIN DENTAL UNIVERSITY HOSPITAL · Jul 18, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether using a special treatment called Leukocyte and Platelet Rich Fibrin (L-PRF) during dental implant placement can improve the stability of the implant and the surrounding bone health. The trial compares traditional implant placement with the use of L-PRF, which is made from a patient’s own blood and helps promote healing by releasing important growth factors. This could potentially help the implant bond better with the bone, leading to a successful outcome.

To be eligible for this study, participants need to be 18 years or older, able to give informed consent, and scheduled for dental implants at Dublin Dental University Hospital. They should also have enough bone volume for the implant without needing additional procedures. However, individuals with high plaque or bleeding scores, smokers, those with uncontrolled health issues, or women who are pregnant or breastfeeding cannot participate. Participants can expect to follow a schedule of appointments and keep a diary of their symptoms throughout the trial to help researchers gather valuable information on the effectiveness of this treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Inclusion Criteria:
• • Patient Level
• • Male or Female, 18 years old or over
• • Capacity to provide informed consent
• • Willing to comply with study appointment schedule Willing to maintain a diary of symptoms
• • Planned for provision of dental implant(s) at Dublin Dental University Hospital Site Level
• • Location: maxilla and mandible
• • Sufficient bone volume for implant placement without the need for bone graft/augmentation; alveolar ridge of minimum 6mm width for standard implants (implant diameter 4mm) and of minimum 7mm for wider implants (implant diameter 5mm)
• Exclusion Criteria:
• • Patient Level
• • Plaque score \>20%
• • Bleeding score \>20%
• • Tobacco smoking
• • Uncontrolled systemic disease
• • Use of systemic medications with an expected impact on bone healing (e.g. bisphosphonates)
• • Pregnancy or lactation
• • lack of capacity to give informed consent
• • Previous radiation to the head and/or neck Site Level
• • Insufficient bone volume for implant placement, requiring bone graft/augmentation