Diluted and Undiluted Enteral Nutrition

Launched by MEDICAL UNIVERSITY OF LUBLIN · Jul 17, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how different types of feeding impact patients after major abdominal surgeries. Specifically, it will compare two methods of enteral nutrition (EN), which is feeding patients directly through their digestive system. One group of patients will receive diluted EN with additional fluids, while the other group will get undiluted EN. The main goal of the study is to see how well patients tolerate these feeding methods, especially in the critical care setting.

To participate in this trial, patients must be scheduled for major abdominal surgery that will require a stay in the Intensive Care Unit (ICU) and must have a functioning gastrointestinal tract for feeding. Unfortunately, those who have had emergency surgeries, cannot provide informed consent, or have certain health conditions that make enteral feeding unsafe won't be eligible. This study is not yet recruiting participants, but it aims to help improve the quality of life for patients who need specialized nutritional support after surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Scheduled for major abdominal surgery requiring ICU admission
• • Having access to the GI tract (gastric or jejunal)
• • Planned to be fed enterally
• Exclusion Criteria:
• • Patients unable to give informed consent
• • After emergency surgeries
• • Without access to the GI tract
• • Individuals with contraindications to EN, such as short bowel syndrome, uncompensated shock, acidosis (pH \< 7.1; lactate \> 5 mmol/l), bleeding from the upper GI tract, obstruction, intestinal ischemia, abdominal compartment syndrome
• • Patients with symptomatic gastro-esophageal reflux
• • Expected ICU stay \< 3 days
• • Pregnancy and lactation