Process-based Therapy for Difficult-to-treat Anxiety Disorders and Depression

Launched by GOETHE UNIVERSITY · Jul 18, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new approach called Process-based Therapy to see how well it works for people with difficult-to-treat anxiety disorders and depression. Researchers want to compare this therapy with traditional cognitive behavioral therapy (CBT) that is commonly used in everyday practice. The goal is to find out which method is more effective for helping patients who have not had success with other treatments.

To participate in this study, you need to be between 18 and 65 years old and have been diagnosed with depression or an anxiety disorder. It’s important that you have already tried at least two different treatments without success. You don't have to stop taking your current medications during the trial, but they need to stay the same throughout the study. If you have certain other mental health conditions, such as severe depression or substance abuse issues, you may not be eligible. If you decide to join, you can expect to receive either Process-based Therapy or the traditional CBT during the study period.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • A primary DSM-5 diagnosis of depressive or anxiety disorder
• • At least two unsuccessful attempts of pharmacological or psychological treatment according to the German guidelines for the treatment of depression or anxiety disorders (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften, AWMF)
• • Age 18-65 years
• • Sufficient knowledge of the German language
• • Participating patients are not required to discontinue medication, but to keep medication constant over the treatment period
• Exclusion Criteria:
• • Increased suicidality
• • Substance abuse or dependency
• • Borderline personality disorder
• • Pervasive developmental disorder
• • Psychotic disorder
• • Eating disorder
• • Bipolar disorder
• • Severe physical illness