A Novel Imaging Modality to Evaluate Radiation-Induced Uterine Injury

Launched by UNIVERSITY OF COLORADO, DENVER · Jul 18, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to look at the uterus using special imaging techniques called shear-wave elastography (SWE) and magnetic resonance imaging (MRI). The main goal is to see if these methods can help doctors identify injuries to the uterus caused by radiation treatment. The study is open to female patients between the ages of 15 and 39 who have been treated for colorectal or anal cancer and received a certain amount of pelvic radiation (at least 50 Gy) at least 12 months ago.

To participate, women must be within the specified age range and have had the radiation treatment mentioned, but those who have had a hysterectomy for a gynecological cancer or are currently pregnant cannot join. If eligible, participants can expect to undergo imaging tests to help researchers understand how effective this new imaging technique is in detecting radiation-related injuries. This study is important as it may improve how we monitor and treat women who have experienced these types of injuries after cancer treatment.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Female
• • 2. 15 ≤ age of treatment \< 40 years
• • 3. Treated with PRT at UCH
• • 4. Received ≥ 50 Gy PRT
• Exclusion Criteria:
• • 1. Patients who underwent hysterectomy for treatment of a primary gynecologic malignancy
• • 2. Patients that are currently pregnant