Establishing Optimal PEEP Setting for Obese Patients in the Steep Trendelenburg Position
Launched by TINASHE MADUKE · Jul 18, 2024
Trial Information
Current as of August 19, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Positive end-expiratory pressure (PEEP) is a measure taken intraoperatively to manage breathing during surgery. The Enlight 2100 is a device that uses electrical impedance tomography (EIT) to measure PEEP and provide a live image of the lungs while a patient is mechanically ventilated. In this study, the investigators will use the Enlight 2100 EIT belt to measure PEEP intraoperatively in order to better optimize PEEP settings for difficult cases.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. BMI ≥ 40 kg/m2
- • 2. Age \> 18 years
- • 3. Scheduled for elective laparoscopic abdominal surgery in the steep Trendelenburg position.
- • 4. Able to provide informed consent.
- Exclusion Criteria:
- • 1. Currently pregnant.
- • 2. Presence of pacemaker, neurostimulator, spinal cord stimulator, or implantable cardioverter-defibrillator.
- • 3. Skin ulcerations on upper torso near the belt placement.
- • 4. Presence of phrenic nerve palsy or other diaphragm conditions.
- • 5. Thoracic circumference \> 134 cm.
- • 6. Tracheomalacia.
- • 7. Inability to speak and understand English.
About Tinashe Maduke
Tinashe Maduke is a dedicated clinical trial sponsor committed to advancing medical research and innovation through rigorous and ethical study designs. With a focus on improving patient outcomes, Tinashe Maduke collaborates with leading healthcare professionals and institutions to conduct high-quality clinical trials across various therapeutic areas. The organization emphasizes transparency, safety, and compliance with regulatory standards, ensuring that all trials are conducted with the highest level of integrity. Through its commitment to scientific excellence and patient-centric approaches, Tinashe Maduke aims to contribute significantly to the development of novel therapies and enhance the overall healthcare landscape.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Columbia, Missouri, United States
Patients applied
Trial Officials
Tinashe Maduke, MD, MPH
Principal Investigator
University of Missouri-Columbia
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported