Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans with Prediabetes

Launched by UNIVERSITY OF CALIFORNIA, IRVINE · Jul 18, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a special diet called the Fasting-Mimicking Diet (FMD) to see if it can help Asian Americans who have prediabetes. The FMD is a carefully designed eating plan that lasts for five days, where participants consume fewer calories and specific nutrients. The main goals of the study are to find out how easy it is to recruit participants and for them to stick with the diet, and to see if this diet can lower blood sugar levels and improve other health measurements.

To participate, you need to be Asian American and diagnosed with prediabetes, which can be identified through certain blood tests. This trial is looking for all adults, but some people may not qualify, such as those with a history of diabetes or certain health conditions. Participants will try the FMD for five days, complete surveys, and attend two study visits to measure their blood sugar and other health indicators before and after the diet. This is an exciting opportunity to contribute to research that could help others manage prediabetes effectively.

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • Identify as Asian American
• * Diagnosed with prediabetes according to at least one of the following:
• • HbA1C 5.7%-6.4%
• • Fasting blood glucose 100 to 125 mg/dL (5.6 to 6.9 mmol/L )
• • Oral glucose tolerance test (OGTT) 140-199 mg/dL at two hours
• Exclusion criteria:
• • Individuals with a personal history of diabetes mellitus (ICD-10 codes E08-E13), cardiovascular disease, mental illness, drug dependency, pregnancy, and special dietary restrictions
• • Individuals taking insulin or insulin-like drugs and individuals taking hypoglycemic agents other than metformin
• • Individuals who are pregnant or breastfeeding
• • Individuals with anaphylaxis food allergies
• • Individuals who are allergic to tree nuts (macadamia, cashew, almond, pecan), soy, oats, sesame, or celery/celeriac
• • Individuals who have completed the FMD in the past year