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Search / Trial NCT06519812

Endoscopic Combined Intrarenal Surgery vs. Percutaneous Nephrolithotomy for Treatment of Staghorn Calculi

Launched by AL-AZHAR UNIVERSITY · Jul 20, 2024

Trial Information

Current as of July 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at two different surgical methods to treat a type of kidney stone called staghorn stones, which can fill up the kidney and cause significant discomfort. The two methods being compared are endoscopic combined intrarenal surgery and percutaneous nephrolithotomy (PCNL). The goal is to see which method is more effective and safer for patients.

To participate in this study, you need to be between 18 and 65 years old and have been diagnosed with staghorn stones based on imaging tests. Unfortunately, certain conditions may prevent you from joining, such as having severe kidney problems, an active urinary infection, or if you are pregnant. If you choose to participate, you will undergo one of the two surgical procedures and be monitored for outcomes related to your treatment. The trial is currently recruiting participants, so if you are interested or think you might qualify, be sure to talk to your healthcare provider for more information.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients are more than 18 and less than 65 years old.
  • Patients with renal staghorn stones based on imaging modalities (stones occupying the renal pelvis and extending into at least 2 major calyces).
  • Exclusion Criteria:
  • Patients with renal insufficiency (serum creatinine \> 1.6 mg/dl)
  • patients with active urinary tract infection.
  • Patients with congenital renal anomalies.
  • Morbid obesity (BMI \> 35 kg/m2).
  • Pregnancy.
  • Bleeding Coagulopathy.
  • Skeletal deformity

About Al Azhar University

Al-Azhar University, a prestigious institution in Egypt, is dedicated to advancing medical research and education through rigorous clinical trials. With a strong emphasis on ethical standards and scientific integrity, the university aims to contribute to the development of innovative therapies and healthcare solutions. By fostering collaboration among researchers, healthcare professionals, and academic experts, Al-Azhar University positions itself as a leading sponsor in clinical research, committed to improving patient outcomes and enhancing the understanding of various medical conditions.

Locations

Damietta, , Egypt

Patients applied

0 patients applied

Trial Officials

Maher Abdelrehem Mohamed, Master

Principal Investigator

assistant lecturer of urology , Al-Azhar University (Damietta)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported