Early Neurovascular Adaptations in Aging Women

Launched by UNIVERSITY OF MISSOURI-COLUMBIA · Jul 22, 2024

Keywords

ClinConnect Summary

This clinical trial, titled "Early Neurovascular Adaptations in Aging Women," is focused on understanding how blood vessels change in response to aging in women. Specifically, it looks at the role of the sympathetic nervous system, which is part of the body's automatic control system that affects things like heart rate and blood flow. The researchers aim to learn more about these changes, especially since they can impact health as women age.

The study is currently recruiting women aged 18 to 55 who were assigned female at birth. However, there are some important requirements to be eligible. For instance, women who are pregnant, breastfeeding, or have certain health conditions may not qualify. Participants can expect to take part in various assessments that will help researchers gather information about their vascular health. This trial is a valuable opportunity to contribute to our understanding of how aging affects women's health, potentially leading to better care and treatments in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Assigned female at birth (AFAB)
• • 18-55 years of age
• Exclusion Criteria:
• • Assigned male at birth (AMAB)
• • Pregnancy, breastfeeding
• • Body mass index ≥30 kg/m2
• • Taking medications known to affect metabolic, autonomic, and/or respiratory function
• • Oral hormonal contraception in last 6 month
• • History of hormone replacement therapy
• • History of hyster- or oophor-ectomy
• • Current smoking/Nicotine use
• • Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy
• • Chronic disease
• • Blood pressure ≥140/90 mmHg
• • Communication barriers