Comparing Photodisinfection of Chitosan NP Enriched ICG Over ICG as Adjunct to OFD: RCT

Launched by KRISHNADEVARAYA COLLEGE OF DENTAL SCIENCES & HOSPITAL · Jul 25, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a new treatment approach for people with periodontitis, a serious gum disease that causes deep pockets in the gums. The researchers want to compare two methods: one uses a special type of light treatment combined with chitosan nanoparticles and indocyanine green (a dye), while the other uses just indocyanine green with a common gum surgery called open flap debridement. The goal is to see which method is more effective in helping to reduce the depth of these gum pockets.

To participate in this study, you need to be between the ages of 30 and 55 and diagnosed with stage II or III grade B/C periodontitis. You should also have pockets in your gums that are at least 5 millimeters deep, even after trying non-surgical treatments. It's important that you are generally healthy and not currently taking antibiotics, have not had gum surgery before, and do not have allergies to the treatments being used. If you join the trial, you'll receive either of the two treatments and help researchers learn more about the best ways to manage gum disease.

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • Systemically healthy subjects
• • Age group 30-55yrs.
• • Diagnosed with Stages II/III grade B/C periodontitis.
• • Presenting with persistent pocket depth ≥5mm after initial non-surgical therapy.
• • Optimal plaque control
• • Good compliance
• Exclusion criteria:
• • Subjects on antibiotic therapy within last six months of enrollment
• • Previous history of periodontal surgery
• • Allergy to drugs and materials used in this study
• • Pregnant woman
• • Subjects with deleterious habits like smoking, tobacco chewing.