Effect of Sodium Bicarbonate, Saline and Black Mulberry Syrup on Degree of Oral Mucositis in Children Receiving Chemotherapy
Launched by BURDUR MEHMET AKIF ERSOY UNIVERSITY · Jul 24, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how different treatments can help reduce oral mucositis, which is a painful condition that can occur in children receiving chemotherapy. Researchers want to compare the effects of sodium bicarbonate, saline (a saltwater solution), and black mulberry syrup on the severity of oral mucositis in children aged 6 to 18 years who are undergoing chemotherapy. The trial aims to find out which of these treatments may be most effective in helping to ease the pain and discomfort associated with this condition.
To participate in the study, children must be between 6 and 18 years old, currently receiving chemotherapy, and able to eat and drink normally. Both the child and their parent or guardian must agree to take part and provide written consent. However, children who already have oral mucositis at the start of the study, have diabetes, are receiving radiation therapy, or have had recent mouth surgery are not eligible. If your child joins the trial, they will receive one of the treatments being tested and will be monitored for any changes in their oral health during their chemotherapy treatment. This study is currently looking for participants, and your involvement could help improve care for other children facing similar challenges.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • The willingness of the family and the child to participate in the study
- • Parent and child have separately informed written consent form
- • Be between 6-18 years old
- • Receiving chemotherapy and being hospitalized for chemotherapy treatment
- • Being fed orally
- Exclusion Criteria:
- • Oral mucositis in the first intraoral evaluation
- • Having diabetes
- • Receiving radiotherapy
- • Having a surgical procedure in the mouth and jaw area
- • Receiving steroid therapy during chemotherapy treatment
- • Using a method other than the methods used in the study to protect the oral mucous membrane throughout the study
About Burdur Mehmet Akif Ersoy University
Burdur Mehmet Akif Ersoy University is a distinguished academic institution committed to advancing medical research and clinical trials. With a focus on innovative healthcare solutions, the university fosters a collaborative environment that integrates cutting-edge scientific inquiry with practical applications. Its dedicated research faculty and state-of-the-art facilities position the institution as a leading sponsor of clinical trials, aimed at enhancing patient outcomes and contributing to the broader medical community. Through rigorous ethical standards and a commitment to excellence, Burdur Mehmet Akif Ersoy University plays a pivotal role in the advancement of medical knowledge and the development of effective therapeutic interventions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Isparta, , Turkey
Patients applied
Trial Officials
Selda Ateş Beşirik, Assistant Professor
Principal Investigator
Burdur Mehmet Akif Ersoy University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported