The Presence of Microplastics and Nanoplastics in the Humans Ileum, Colon, and Rectum and Their Relation With Inflammatory Bowel Disease (IBD)

Launched by PIERPAOLO SILERI · Jul 26, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at the presence of very tiny plastic particles, known as microplastics and nanoplastics, in parts of the human digestive system, specifically the ileum, colon, and rectum. Researchers want to find out if these particles are linked to Inflammatory Bowel Disease (IBD), which is a condition that causes inflammation in the intestines. The study will involve 102 patients who are scheduled to have bowel surgery that includes removing parts of the intestine.

To participate in this trial, patients need to be 18 years or older and must agree to take part by signing an informed consent form. They should be undergoing surgery involving the resection (removal) of the colon, ileum, or rectum for any medical reason. During the study, participants will undergo tests to check for the presence of these plastic particles and will also provide information about their daily exposure to plastics. This research aims to better understand the potential effects of plastic on gut health and might help improve future treatments for IBD.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients who will undergo any type of bowel surgery due to any type of clinical condition, as established by normal clinical practice, where colon, ileum and/or rectum resection is involved.
• • Patients aged ≥ 18 years.
• • Patients who have read, understood, accepted, and signed the informed consent to the study.
• • Female patients within and outside of childbearing age (breastfeeding women can be included in the study)
• Exclusion Criteria:
• • Patients aged \< 18 years.
• • Pregnant women.
• • Patients who have not accepted informed consent.