Regenerative Endodontic Therapy in Cases of Irreversible Pulpitis

Launched by SHAHEED ZULFIQAR ALI BHUTTO MEDICAL UNIVERSITY · Jul 26, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment approach for patients with a painful dental condition called irreversible pulpitis, which means the inner part of the tooth is damaged and cannot heal on its own. Instead of the traditional root canal treatment, which can sometimes lead to further tooth weakening and is often lengthy and costly, this trial is exploring a method called regenerative endodontic treatment (RET). This innovative technique aims to help the tooth heal and regain its strength by using natural substances like stem cells and growth factors, potentially offering a less invasive option with better long-term outcomes.

To participate in this trial, patients need to be between 18 and 35 years old and have a specific type of tooth with mature roots that is still restorable. Those who are pregnant, have serious health issues, or certain dental problems are not eligible. Participants can expect a thorough evaluation and treatment that focuses on promoting healing in their affected tooth. This trial is currently recruiting patients, aiming to provide new insights into how best to treat this common dental issue while minimizing the risks associated with traditional methods.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients from both genders with an age range of 18-35 years old.
• • Permanent teeth with mature roots with a diagnosis of irreversible pulpitis, with absorption damage to the apex, and the diameter of the apical hole is greater than 1 mm.
• • A restorable tooth.
• • There is no need to leave space for the final post/core restoration.
• • Anterior teeth and premolars with single canal.
• • A cooperative and compliant patient.
• • Patients not allergic to the drugs and antibiotics which needed to complete treatment.
• • No periodontal disease or root cracking.
• Exclusion Criteria:
• • Patients with other serious organ diseases, such as cardiopulmonary, kidney and other major diseases.
• • Pregnant women or lactating or expecting within a year.
• • Patients with apical cysts.
• • Patients with poor cooperation and those who quit the study halfway.
• • Patients with periodontitis.
• • Patients with dental dysplasia or other oral genetic disorders.
• • Patients with dental phobia.
• • Patients with mental disorders.