Investigation of the Effect of Movement Mobilization Concept on Sensory, Pain, Muscle Activation in Patients With Knee Osteoarthritis
Launched by ISTINYE UNIVERSITY · Jul 25, 2024
Trial Information
Current as of July 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is exploring the effects of a special movement technique called the Mulligan movement mobilization concept on patients with knee osteoarthritis. Osteoarthritis is a condition that causes pain and stiffness in the joints, particularly in the knees, making it hard for people to move around and perform daily activities. The study aims to measure changes in pain levels, muscle activity, and sensory perception (how the body senses movement and pain) to see how this movement technique can help improve quality of life for those affected by knee osteoarthritis.
To participate in this trial, individuals should be between the ages of 50 and 70 and have been diagnosed with knee osteoarthritis for at least six months. They should be able to walk without help, have a specific range of pain levels, and meet certain health criteria. Participants will undergo assessments to evaluate their pain, muscle function, and sensory responses. This information will help researchers understand how effective the movement technique is and guide future treatments for knee osteoarthritis. If you or a loved one is considering participating, it’s a great opportunity to contribute to research that could lead to better management of this condition.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Diagnosing knee OA according to the American College of Rheumatology (ACR) criteria (Primary knee OA diagnosis)
- • Stage 2 or 3 patients according to Kellgren-Lawrence radiological staging criteria
- • Patients with a disease duration of 6 months or longer
- • Participants aged between 50 and 70
- • Being able to walk without using assistive devices
- • Body mass index is below 35 kg/m²
- • Pain intensity must be between 3 and 7 according to the Numerical Pain Rating Scale
- • Not having received physiotherapy in the last year.
- Exclusion Criteria:
- • Infiltration with steroids or local anesthetics in the year before the patient entered the study or during follow-up
- • Obtaining the indication for surgery
- • Severe hearing, vision and speech impairment
- • Having serious systemic and cardiovascular diseases that prevent exercise
- • Having a neurological disease
- • Having a lower extremity deformity (severe varus or valgus deformity, significant joint instability and other orthopedic problems requiring surgical intervention)
- • Patients with acute knee inflammation
- • Having any disorder, syndrome or disease that may cause myofascial or neuropathic pain in the lower extremities, such as lumbar radiculopathy, meralgia paresthetica or Saphenous nerve compression.
- • Cognitive deficit (Alzheimer's, dementia) revealed in the clinical history.
About Istinye University
Istinye University is a leading academic institution committed to advancing medical research and education. With a strong emphasis on innovation and collaboration, the university actively engages in clinical trials that aim to enhance healthcare outcomes and contribute to scientific knowledge. Leveraging its state-of-the-art facilities and a team of experienced researchers and clinicians, Istinye University fosters a rigorous environment for conducting high-quality clinical studies across various medical disciplines. The institution is dedicated to ethical practices and patient safety, ensuring that all research initiatives align with the highest standards of integrity and scientific excellence.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Istanbul, , Turkey
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported