AI-Powered ECG Detecting Culprit Vessel Blood Flow Abnormality in ACS

Launched by POWERFUL MEDICAL · Jul 26, 2024

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ClinConnect Summary

This clinical trial, called AI ECG TIMI, is studying how an advanced artificial intelligence (AI) model can help doctors identify problems with blood flow in the heart of patients experiencing acute coronary syndrome (ACS). ACS includes serious conditions like heart attacks (STEMI and NSTEMI), where blood supply to the heart is suddenly reduced or blocked. The goal is to see if the AI can analyze electrocardiograms (ECGs)—a test that measures the electrical activity of the heart—and predict issues in blood flow just before a procedure called invasive coronary angiography, which doctors use to look at the heart's blood vessels.

To participate in this trial, patients need to be at least 18 years old and must be experiencing symptoms of ACS that require emergency medical attention, leading to an invasive coronary angiography. However, those who are having non-emergency procedures or have chronic heart problems won't be included. If eligible, participants can expect to have a standard ECG done shortly before their angiography, allowing researchers to gather important information about how well the AI can work in real-life situations. This study is currently recruiting participants from various locations, aiming to improve how doctors diagnose and treat heart conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with acute coronary syndromes undergoing invasive coronary angiography as clinically indicated.
• • Availability of a standard 12-lead ECG performed at invasive coronary angiogram before percutaneous coronary intervention (maximum within 15 min before vascular access).
• • Age ≥18 years.
• Exclusion Criteria:
• • Individuals presenting for a non-emergent (elective) cardiac catheterization.
• • Individuals presenting with chronic coronary syndrome (CCS) or stable angina symptoms.
• • Individuals without symptoms suspicious for acute coronary syndromes.
• • Individuals with contraindications for cardiac catheterization.