Skin Wetting in Burn Survivors

Launched by UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER · Jul 26, 2024

Keywords

ClinConnect Summary

The "Skin Wetting in Burn Survivors" clinical trial is studying how wetting the skin can help burn survivors manage their body temperature during exercise, especially in hot conditions. Researchers want to find out if this method can reduce overheating in people who have had burns covering different areas of their bodies. The study involves comparing those with burn injuries to healthy individuals who have not experienced burns.

To participate, you need to be between 18 and 65 years old and in good health. Burn survivors must have had burns covering 20-40% or more than 40% of their body, with at least some of those burns requiring skin grafts and a hospital stay of at least 15 days. If you join the study, you will exercise in a warm environment while either receiving no cooling or having your skin wetted, allowing researchers to see which method works better to keep your body temperature in check. This study is important because it could lead to better ways for burn survivors to stay safe and comfortable during physical activities.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria: Non-burn survivors
• • Healthy male and female subjects
• • 18-65 years of age.
• • Free of any underlying medical conditions
• Exclusion Criteria (non-burned individuals):
• • Any burn-related injuries resulting in at least one night of hospitalization.
• • Heart disease or any other chronic medical condition requiring regular medical therapy including cancer, diabetes, and hypertension.
• • Abnormalities detected on routine screening
• • Individuals who participate in a structured aerobic exercise training program at moderate to high intensities.
• • Current smokers, as well as individuals who regularly smoked within the past 3 years.
• • Body mass index of greater than 30 kg/m\^2.
• • Pregnant individuals
• Inclusion Criteria (burn survivors):
• • Healthy male and female subjects
• • 18-65 years of age.
• • Free of any underlying medical conditions
• • Having a burn injury covering 20-40% or \>40% of the participant's body surface area; at least 50% of those burn injuries must be full thickness that required skin grafting.
• • Participants must have been hospitalized due to the burn injury for a minimum of 15 days
• Exclusion Criteria (burn survivors):
• • Any burn-related injuries resulting in at least one night of hospitalization.
• • Heart disease or any other chronic medical condition requiring regular medical therapy including cancer, diabetes, and hypertension.
• • Abnormalities detected on routine screening
• • Individuals who participate in a structured aerobic exercise training program at moderate to high intensities.
• • Current smokers, as well as individuals who regularly smoked within the past 3 years.
• • Body mass index of greater than 30 kg/m\^2.
• • Pregnant individuals
• • Extensive unhealed injured skin