Pressure Pain Tolerance in Relation to Balance and Strength in Children
Launched by ADLY A ADAM · Jul 29, 2024
Trial Information
Current as of July 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how pain tolerance relates to balance and muscle strength in children with sickle cell anemia. Sickle cell anemia is a condition where the body produces abnormal red blood cells that can cause pain and other health issues. The researchers want to understand how exercise can help these children improve their physical abilities and manage pain better, especially since there aren’t clear guidelines on safe exercises for them.
To participate in the study, children must be between 9 and 14 years old, stable on their medications, and have experienced chronic pain for at least six months. They should also be of average weight and height for their age. Children with certain health conditions, like heart or lung problems, or those who have had recent surgeries, cannot participate. If eligible, participants can expect to engage in activities that will help assess their pain tolerance, balance, and strength, contributing to future exercise recommendations for kids with sickle cell anemia.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age range range was 9-14 years old.
- • Could follow given instructions.
- • Children with Sickle cell anemia were medically stable, and take their medications regularly.
- • Children with Sickle cell anemia had experience of chronic pain that lasts more than 6 months.
- • All children with Sickle cell anemia have average weight, height, and body mass index based on their age percentiles.
- • All normal healthy children did not participating in regular sport activities, particularly including lower limb strengthening.
- Exclusion Criteria:
- • Defined cardiovascular or respiratory disorders.
- • Renal failure.
- • Myocardial infarction, mainly within last month.
- • Unstable angina.
- • Recent thoracoabdominal surgery.
- • Thoracic or abdominal aneurysm or current pneumothorax.
- • Painful vaso-occlusive crises.
- • Muscular contractures, Joints' stiffness, or deformities.
- • Neuromuscular problems i.e., myositis or peripheral neuropathy.
About Adly A Adam
Adly A. Adam is a distinguished clinical trial sponsor specializing in the development and oversight of innovative therapeutic solutions. With a commitment to advancing medical research, the organization focuses on conducting rigorous clinical trials that adhere to the highest ethical standards and regulatory guidelines. Leveraging a robust network of healthcare professionals and research institutions, Adly A. Adam aims to facilitate the discovery of new treatments and improve patient outcomes across various therapeutic areas. Their dedication to scientific excellence and collaboration ensures that they remain at the forefront of clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Giza, , Egypt
Patients applied
Trial Officials
Shimaa A Ahmed, PHD
Study Chair
Head of Haematology Dept, Faculty of Medicine, Alexandria University
Elham M Salem, PHD
Study Director
Professor of Physical Therapy, Faculty of Physical Therapy, Cairo University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported