Multimodality US Based on Angio Planewave Ultrasensitive Imaging and Shear Wave Elastography to Evaluate the Malignancy Risk Value of Thyroid Nodules

Launched by FIFTH AFFILIATED HOSPITAL, SUN YAT-SEN UNIVERSITY · Jul 30, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new way to use ultrasound technology to help doctors tell the difference between harmless (benign) and harmful (malignant) thyroid nodules. It uses advanced imaging techniques, including a special type of ultrasound called Angio Planewave Ultrasensitive Imaging and another method called Shear Wave Elastography, along with standard grayscale ultrasound. The main aim is to see if these combined methods can improve the accuracy of diagnosing thyroid nodules and guide doctors in deciding if a needle biopsy is needed.

To participate in this trial, individuals must be over 18 years old, have at least one thyroid nodule that can be seen on an ultrasound, and be willing to undergo surgery to confirm the results. Participants will have a series of ultrasound tests within a week before their surgery. It’s important to note that those with certain conditions, like large calcifications in the nodules or a history of neck surgery or cancer, may not be eligible. This research could lead to better ways of diagnosing thyroid issues, which is important for ensuring patients get the right treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. age more than 18 years;
• • 2. Voluntarily signed informed consent;
• • 3. Have 1 or more thyroid nodules detectable by ultrasound;
• • 4. participant underwent surgical procedure to confirm the pathologic results
• Exclusion Criteria:
• • 1. Nodules are accompanied by large calcifications followed by acoustic shadows
• • 2. History of previous neck surgery or cancer, thyroid medications, radiation or surgical treatment;
• • 3. Poor quality of retained images or non-standard operations (such as intermittent scanning and improper probe compression), and incomplete pathological results.