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Search / Trial NCT06533371

Clinical-ultrasonographic Assessment of Pulmonary Emphysema

Launched by FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS · Jul 29, 2024

Trial Information

Current as of May 22, 2025

Recruiting

Keywords

Pulmonary Emphysema Emphysema Lung Ultrasound Oscillometry Quantitative Analysis Chest Computed Tomography Early Diagnosis

ClinConnect Summary

This clinical trial is looking at how well lung ultrasound (LUS) can help us understand changes in the lungs of patients with emphysema, a condition that affects breathing. The researchers want to see how the patterns seen in LUS compare to those found using a special type of X-ray called high-resolution computed tomography (HRCT). They will study patients with different types of emphysema and compare their results with healthy individuals and those without emphysema. This could lead to better ways of detecting and monitoring lung diseases.

To be eligible for this trial, participants must be adults aged 65 to 74 with stable or worsening emphysema, or they may be part of a lung cancer screening program. They need to be able to give written consent to take part. During the study, participants will receive a lung ultrasound while lying down, similar to the position used for the CT scans. They will also undergo a breathing test that provides important information about lung health. Overall, this trial aims to improve our understanding of emphysema through non-invasive testing methods.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • outpatients in follow-up for chronic obstructive pulmonary disease, in stable conditions, with computed tomographic evidence of panlobular or paraseptal emphysema.
  • Inpatients, admitted to the hospital due to acute exacerbation of chronic obstructive pulmonary disease, with computed tomographic evidence of panlobular or paraseptal emphysema.
  • Subjects who participate in the screening program for lung cancer with computed tomographic evidence of panlobular or paraseptal emphysema.
  • Outpatients / Inpatients with suspected/known lung cancer and computed tomographic evidence of panlobular or paraseptal emphysema.
  • Patients able to give written informed consent.
  • Exclusion Criteria:
  • pregnancy.
  • Pediatric population.
  • Patients unable to express written informed consent.

About Fondazione Policlinico Universitario Agostino Gemelli Irccs

Fondazione Policlinico Universitario Agostino Gemelli IRCCS is a leading research and healthcare institution based in Rome, Italy, renowned for its commitment to advancing medical science and improving patient care. As a prominent academic medical center affiliated with the Catholic University of the Sacred Heart, it integrates clinical practice, education, and research, fostering innovation in various fields of medicine. The foundation conducts a wide range of clinical trials aimed at developing new therapies and enhancing treatment protocols, with a focus on translational research that bridges the gap between laboratory discoveries and patient care. Its multidisciplinary approach and dedication to high ethical standards position it as a key player in the landscape of clinical research and healthcare improvement in Italy and beyond.

Locations

Napoli, , Italy

Rome, Roma, Italy

Acquaviva Delle Fonti, , Italy

Trento, , Italy

Patients applied

0 patients applied

Trial Officials

Riccardo Inchingolo, MD, PhD

Principal Investigator

Fondazione Policlinico Universitario A. Gemelli, IRCCS

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported