Measuring Brain Health Using Low-Field Portable MRI

Launched by YALE UNIVERSITY · Jul 29, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new way to measure brain health, specifically focusing on a condition called White Matter Hyperintensity (WMH). WMH refers to changes in the brain's white matter, which can be affected by various health issues. The researchers are developing a grading scale and using a special type of MRI called low-field MRI to help measure the volume of WMH more accurately. This could help doctors better understand brain health and the impact of conditions like high blood pressure, high cholesterol, or diabetes.

To participate in this study, individuals aged 18 and older who have at least one vascular risk factor, such as high blood pressure, high cholesterol, or diabetes, may be eligible. However, people with a history of stroke, dementia, or certain medical devices like pacemakers cannot join. Participants will undergo MRI scans and help researchers gather important data to improve brain health assessments. If you or someone you know fits the eligibility criteria and is interested in contributing to this research, it could be a valuable opportunity to help advance our understanding of brain health.

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Eligibility criteria

• Inclusion Criteria:
• * One vascular risk factor, from the following:
• • 1. Hypertension (defined as taking an antihypertensive medication)
• • 2. Hyperlipidemia (defined as taking a statin or PCSK9 inhibitor)
• • 3. Diabetes (defined as taking a medication to prevent hyperglycemia)
• Exclusion Criteria:
• • 1. History of stroke
• • History of dementia or other cognitive impairment
• • Pacemaker or other MRI contraindications according to the American College of Radiology guidelines