Evaluation of the Relationship Between OND and ONSD Measured by TOS With Clinical, Radiological, and Electrophysiological Parameters in MS Patients

Launched by KUTAHYA HEALTH SCIENCES UNIVERSITY · Jul 30, 2024

Keywords

ClinConnect Summary

The study included 102 patients with MS-81 with relapsing-remitting MS (RRMS), 19 with secondary progressive MS (SPMS), and 2 with primary progressive MS (PPMS)-as well as 34 healthy controls, all selected according to the inclusion and exclusion criteria. Demographic data for all participants, and clinical characteristics of the MS patient group, were recorded. Expanded Disability Status Scale (EDSS) measurements were performed for the patients. Then, TOS, orbital MRI, VEP and OCT examinations were applied to the individuals in the patient group on the same day for each eye. Measurements r...

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Eligibility criteria

• Inclusion Criteria:
• • Being between the ages of 18-65
• • Having been diagnosed with Multiple Sclerosis
• • Undergoing disease-modifying therapy (DMT) for more than 6 months
• • EDSS score ≤ 7
• Exclusion Criteria:
• • Patients whose Multiple Sclerosis diagnosis is uncertain
• • Having ocular pathology that may affect optic nerve measurements (e.g., glaucoma, high myopia, history of ocular surgery)
• • Having major systemic diseases that may affect optic nerve measurements (e.g., diabetes mellitus, hypertension)
• • EDSS score \> 7
• • Having experienced a clinical relapse or optic neuritis within the last 6 months.