Digital Diagnostics and Intervention Services for Parkinson's Disease

Launched by UNIVERSITY OF EXETER · Jul 29, 2024

Keywords

ClinConnect Summary

This clinical trial is studying new digital tools to help assess and improve the movement of people with Parkinson's disease. Currently, patients see their doctors only once every 12 to 18 months, and during those visits, a long assessment called the UPDRS is used to check their health and how the disease is progressing. The goal of this study is to see if two new devices—one that measures eye movements and another that tracks walking—can provide a more frequent and accurate assessment, both in the clinic and at home. Additionally, participants will try a new home physiotherapy program that aims to improve walking over two weeks.

To be eligible for this study, participants must be at least 18 years old and have a diagnosis of Parkinson's disease or certain other conditions affecting movement. They should be able to walk for at least 5 minutes, either on their own or with assistance. Healthy adults can also join the study if they meet specific criteria. Participants can expect to use the new devices and participate in home therapy sessions, helping researchers gather important information on how these digital solutions can support people with Parkinson's in their daily lives.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of idiopathic Parkinson's disease (UK Brain Bank Criteria) or other appropriate condition specific scale \[stroke, multiple sclerosis, arthritis or osteoporosis\]
• • Able to self-report history of daily gait freezing and/or festination for people with PD or gait and/or transfers affected by condition
• • Able to walk unsupported or using an aid for at least 5 minutes and satisfactory completion of the Canadian PARQ and if over 69 used to carrying out this level of exercise
• • Adult (+18 years old)
• • Normal or corrected-to-normal vision (Snellen Visual Acuity \> 12/18) or safe to mobilise with support
• • Montreal Cognitive assessment score \>21 or ability to follow 2 stage commands Healthy participants \[Phase 1,2,3\]
• • With no long-term conditions affecting movement
• • Able to walk unsupported or using an aid for at least 3 minutes and satisfactory completion of the Canadian PARQ and
• • if over 69 used to carrying out this level of exercise
• • Adult (+18 years old)
• • Normal or corrected-to-normal vision (Snellen Visual Acuity \> 12/18) or safe to mobilise with support
• • Montreal Cognitive assessment score \>21 or ability to follow 2 stage commands
• Exclusion Criteria:
• • Participants with long-term conditions affecting movement
• • Any physical or mental condition affecting ability to safely participate in this level of activity and capacity to understand
• • testing as demonstrated by ability to safely follow commands and pass the PARQ by the research team.
• • Cognitive impairment affecting ability to safely participate and follow instructions
• • Any injury or disorder that may affect balance (other than Parkinson's or referring primary condition)
• • Any skin conditions or broken skin in the calf and behind knee area
• • Deep brain stimulation or pacemaker implants or other implant that may interfere with the measurement system Healthy participants
• • Any physical or mental condition affecting ability to safely participate in this level of activity and capacity to understand
• • testing as demonstrated by ability to safely follow commands and pass the PARQ by the research team.
• • Cognitive impairment affecting ability to safely participate and follow instructions
• • Any injury or disorder that may affect balance (other than Parkinson's or referring primary condition)
• • Any skin conditions or broken skin in the calf and behind knee area
• • Deep brain stimulation or pacemaker implants or other implants that may interfere with the measurement system