The Influence of Sleep on Cardiovascular Outcomes

Launched by OREGON HEALTH AND SCIENCE UNIVERSITY · Jul 31, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how sleep patterns affect heart health. Researchers want to find out if having a regular sleep schedule can lead to better metabolic and vascular health, which relates to how our bodies manage energy and blood flow. The study will last for 12 weeks and will involve both in-home and lab assessments. They are currently recruiting healthy adults aged 18 to 40, both men and women, to participate in this important research.

To be eligible, participants must be generally healthy and cannot have a history of substance abuse, smoking, or certain medical conditions like heart disease, high blood pressure, diabetes, or sleep disorders. They should also not have worked irregular hours or traveled across time zones in the months leading up to the study. Those who choose to participate can expect to contribute to our understanding of how sleep impacts heart health, helping to improve health recommendations for everyone in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Ostensibly healthy men and women
• Exclusion Criteria:
• • No history of drug or alcohol dependency.
• • Must be current non-smokers, and are required to have a history of less than 5 pack years of smoking.
• • No history of working irregular day and night hours, regular night work, or rotating shift work for the 1 year prior to the study. In addition to this, individuals must not have traveled across more than 1 time zone during the 3 months prior to the study.
• • Chronobiologic and sleep disorders.
• • Diseases of the cardiovascular system.
• • Hypertension. Individuals will be allowed to be normotensive (resting systolic blood pressure of \<140/90 mmHg, measured on more than one occasion) or uncomplicated stage 1 hypertension (systolic BP between 140 and 159 mmHg or a diastolic BP between 90 and 99 mmHg).
• • Disorders of the respiratory system.
• • Pre-diabetes/Diabetes. For participants who have self-reported pre-diabetes/diabetes.
• • Disorders of the kidney and urinary tract.
• • Infectious diseases.
• • Disorders of the gastrointestinal system.
• • Disorders of the immune system.
• • Disorders of the hematopoietic system.
• • Neoplastic diseases.
• • Endocrine and metabolic diseases.
• • Neurologic disorders.
• • Must not be participating in another research study that would influence their safe participation in the study.