Trigeminal Brainstem Mapping 2: Higher Cortical Strucureas As Well As Subnuclei of the Spinal Trigeminal Nucleus

Launched by UNIVERSITÄTSKLINIKUM HAMBURG-EPPENDORF · Jul 30, 2024

Keywords

ClinConnect Summary

This clinical trial, called "Trigeminal Brainstem Mapping 2," is studying how different parts of the brain respond to stimulation of the trigeminal nerve, which is often involved in migraine disorders. Researchers want to learn more about how the brain processes pain signals and other sensations related to this nerve by using advanced imaging techniques. They will scan the entire brain, brainstem, and upper spinal cord while participants experience both painful and non-painful electrical stimulation of the trigeminal nerve and the arm as a comparison.

To participate in this study, you need to be healthy and able to undergo an MRI scan. Unfortunately, individuals with headache disorders, psychological conditions, or who are pregnant cannot take part. If eligible, participants can expect to undergo brain scans while receiving safe electrical stimulation, helping researchers gain valuable insights into the mechanisms of migraine and related conditions. This study is currently recruiting participants aged between 18 and 65.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • healthy
• • suitable fo MRI
• Exclusion Criteria:
• • headache disease
• • psychological disorder
• • pregnancy
• • all exclusion criteria necessary for imaging in a 3 T MRI scanner