Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

Launched by BRIGHAM AND WOMEN'S HOSPITAL · Jul 31, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new technology called portable dynamic digital radiography (DDR) in the Intensive Care Unit (ICU). DDR is an advanced type of chest X-ray that takes images at a fast rate, allowing doctors to see how the lungs are moving and functioning in real-time. The goal of the trial is to find out if this portable DDR machine is safe and effective for patients in the ICU compared to traditional imaging methods like standard X-rays and CT scans.

To participate in this study, patients must be adults (18 years or older) who may have issues with their lung function or breathing, and they can be either on a ventilator or breathing on their own. Participants will receive one to three sets of images taken with the portable DDR machine, and their results will be compared to standard tests to see how accurate the new technology is in assessing lung health. It's important to note that certain individuals, such as pregnant women or those who cannot safely receive additional radiation, will not be eligible to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria: Participants must meet all the following inclusion criteria to participate in this study:
• • Adults (at least 18 years of age) including both intubated/ventilated and non-intubated patients
• • Likely to have pathology related to either, abnormal diaphragmatic excursion and lung aeration, pulmonary perfusion, increased lung water content or all the above, as well as for cricopharyngeal dysfunction/swallowing difficulties at risk for aspiration.
• • The subject or a legally authorized representative has provided written informed consent.
• Exclusion Criteria: Candidates meeting any of the exclusion criteria at baseline will be excluded from study participation. These criteria are:
• • Special populations, including women with known pregnancy, prisoners, or institutionalized individuals
• • Patients where additional radiation is clinically contraindicated
• • Care team does not provide assent for approaching patient/surrogate
• • For women of child-bearing potential, defined as premenopausal women, a pregnancy test will be administered to determine pregnancy status and confirm eligibility for the study. A pregnancy test will NOT be administered to women who are post-menopausal or have documentation of surgical sterilization.