Efficacy of Light Therapy in Treatment of Chronic Cluster Headache

Launched by ASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE · Aug 2, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the use of light therapy as a potential treatment for chronic cluster headaches, which are severe headaches that occur frequently and can be very hard to manage. Light therapy has been used successfully for other conditions like seasonal depression and migraines, and researchers want to see if it can help with the pain and frequency of cluster headaches by helping to reset the body’s natural rhythms.

To participate, you need to be at least 18 years old and have a diagnosis of chronic cluster headache, experiencing at least one headache attack per day. You should also have been stable on your current headache medication for at least a month and be able to communicate in French. Participants will use a light therapy device at home, and the study will assess how well this treatment works over time. It’s important to note that certain medical conditions or treatments may prevent you from participating, so be sure to discuss your individual health status with the study team.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or female, of 18 years years old or more;
• • Diagnosis of chronic cluster headache according to ICHD-3 criteria;
• • Number of seizures during baseline equal to at least 24;
• • Stability of prophylactic treatment for at least 1 month and commitment not to change it for the duration of the study;
• • Patient affiliated to the French social security system.
• • Patient who understands and speaks French correctly;
• • Patient who has given free and informed written consent.
• Exclusion Criteria:
• • Contraindication to the use of light therapy: use of a photosensitizing treatment;
• • Ophthalmological history: cataract, macular degeneration, glaucoma, retinitis pigmentosa;
• • Patients who work at night;
• • Other neurological, psychiatric or developmental pathologies considered incompatible with the study;
• • Background treatment of cluster headache with melatonin;
• • Persons protected by articles L1121-5, L1121-6 and L1121-8 of the French Public Health Code (pregnant or breast-feeding women, persons deprived of their liberty by judicial decision, socially vulnerable persons, adults incapable or unable to express their consent).