ClinConnect ClinConnect Logo
Search / Trial NCT06540794

Evaluating Respiratory Effects of Driving Pressure Guided Mechanical Ventilation Using Electrical Impedance Tomography in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy

Launched by ISTANBUL UNIVERSITY · Aug 2, 2024

Trial Information

Current as of June 27, 2025

Enrolling by invitation

Keywords

Driving Pressure Electrical Impedance Tomography Robot Assisted Laparoscopic Prostatectomy Peep Titration Recruitment

ClinConnect Summary

General anesthesia increases the risk of respiratory complications and impairs arterial oxygenation by causing atelectasis in the dorsal regions of the lungs. Postoperative pulmonary complications (PPC) represent events such as atelectasis, pulmonary edema, pneumonia, pleuritis, reintubation, and the need for oxygen support after surgery, and are associated with increased morbidity, mortality, intensive care, and hospital stay durations, as well as higher healthcare costs. The effective strategy to reduce the incidence of PPC in patients under general anesthesia is still not clear.

Robot-a...

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • ASA score of I-II-III according to the American Society of Anesthesiologists (ASA) physical status classification system
  • Surgery duration is expected to be longer than 2 hours
  • Exclusion Criteria:
  • Patients who underwent surgery requiring mechanical ventilation for more than 1 hour within 2 weeks before the operation
  • Patients with a body mass index over 35
  • Patients with large bullae or pneumothorax, those currently receiving oxygen support, those with severe respiratory disease
  • Patients with severe heart failure classified as NYHA class III-IV by the New York Heart Association (NYHA), those with a pacemaker or cardiac defibrillator implant
  • Patients with progressive neuromuscular disease
  • Patients who refused to participate in the study were excluded.

About Istanbul University

Istanbul University, a leading institution in Turkey, is dedicated to advancing healthcare through rigorous clinical research and education. Renowned for its commitment to scientific excellence and innovation, the university sponsors clinical trials that aim to enhance medical knowledge and improve patient outcomes. With a diverse team of researchers and healthcare professionals, Istanbul University fosters collaboration across disciplines to explore new therapeutic interventions and contribute to global health advancements. Its robust infrastructure and ethical standards ensure the highest quality in clinical trial management, making it a key player in the field of medical research.

Locations

Istanbul, , Turkey

Patients applied

0 patients applied

Trial Officials

Ezgi B Ozyalcın, Medical Doctor

Principal Investigator

Istanbul University - Cerrahpasa

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported