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Search / Trial NCT06542276

Single Lipiflow Treatment to Reduce Pharmacologic Burden in DED

Launched by DUNES EYE CONSULTANTS · Aug 4, 2024

Trial Information

Current as of July 09, 2025

Enrolling by invitation

Keywords

ClinConnect Summary

Prospective, non-randomized, interventional study. Subjects with bilateral use of a topical immunomodulator drop and a history of dry eye disease were recruited to participate. All subjects underwent a vectored thermal pulsation treatment (LipiFlow). Patients were seen at baseline in a visit immediately prior to treatment and at months 1 and 3 following treatment. Data collected included tear osmolarity, tear break up time (TBUT), tear meniscus height (TMH), meibomian gland function and patient-reported symptoms using the ocular surface disease index (OSDI) questionnaire. Following the 3-mo...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • No prior history of meibomian gland treatment procedures LipiFlow, TearCare, or I-Lux
  • lifitegrast or cyclosporine eye drops daily for a period of at least one year but not exceeding five years
  • Meibograpy documneted retention of at least 50% of meibomian glands.
  • Exclusion Criteria:
  • evidence of meibomian gland dropout exceeding 50%
  • ocular rosacea,
  • ocular surgery within the preceding three months
  • prior in-office thermal meibomian gland treatment
  • ocular trauma within preceding three months
  • ocular herpetic infection
  • chronic or recurrent inflammation
  • eyelid abnormalities affecting lid function ocular surface abnormalities compromising corneal integrity (eg, epithelial basement membrane dystrophy, corneal burn)
  • pregnant

About Dunes Eye Consultants

Dunes Eye Consultants is a leading clinical trial sponsor specializing in innovative ophthalmic research and development. Committed to advancing eye care, the organization collaborates with top-tier researchers and healthcare professionals to conduct rigorous clinical trials aimed at evaluating new therapies and technologies for various ocular conditions. With a focus on patient safety and ethical standards, Dunes Eye Consultants strives to enhance treatment options and improve outcomes for individuals suffering from vision-related disorders, ensuring that cutting-edge solutions are effectively brought to market.

Locations

Dakota Dunes, South Dakota, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported