Single Lipiflow Treatment to Reduce Pharmacologic Burden in DED
Launched by DUNES EYE CONSULTANTS · Aug 4, 2024
Trial Information
Current as of July 09, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Prospective, non-randomized, interventional study. Subjects with bilateral use of a topical immunomodulator drop and a history of dry eye disease were recruited to participate. All subjects underwent a vectored thermal pulsation treatment (LipiFlow). Patients were seen at baseline in a visit immediately prior to treatment and at months 1 and 3 following treatment. Data collected included tear osmolarity, tear break up time (TBUT), tear meniscus height (TMH), meibomian gland function and patient-reported symptoms using the ocular surface disease index (OSDI) questionnaire. Following the 3-mo...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • No prior history of meibomian gland treatment procedures LipiFlow, TearCare, or I-Lux
- • lifitegrast or cyclosporine eye drops daily for a period of at least one year but not exceeding five years
- • Meibograpy documneted retention of at least 50% of meibomian glands.
- Exclusion Criteria:
- • evidence of meibomian gland dropout exceeding 50%
- • ocular rosacea,
- • ocular surgery within the preceding three months
- • prior in-office thermal meibomian gland treatment
- • ocular trauma within preceding three months
- • ocular herpetic infection
- • chronic or recurrent inflammation
- • eyelid abnormalities affecting lid function ocular surface abnormalities compromising corneal integrity (eg, epithelial basement membrane dystrophy, corneal burn)
- • pregnant
About Dunes Eye Consultants
Dunes Eye Consultants is a leading clinical trial sponsor specializing in innovative ophthalmic research and development. Committed to advancing eye care, the organization collaborates with top-tier researchers and healthcare professionals to conduct rigorous clinical trials aimed at evaluating new therapies and technologies for various ocular conditions. With a focus on patient safety and ethical standards, Dunes Eye Consultants strives to enhance treatment options and improve outcomes for individuals suffering from vision-related disorders, ensuring that cutting-edge solutions are effectively brought to market.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Dakota Dunes, South Dakota, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported