A Study for Dynamic Prediction Model of Breast Cancer Bone Metastases

Launched by CANCER INSTITUTE AND HOSPITAL, CHINESE ACADEMY OF MEDICAL SCIENCES · Aug 5, 2024

Keywords

ClinConnect Summary

This clinical trial aims to understand the risk factors that can lead to bone metastases in patients with breast cancer. Bone metastases occur when cancer spreads from the breast to the bones, which can affect treatment plans and patient outcomes. By collecting and analyzing real-world data from multiple medical centers, researchers hope to create a tool that helps healthcare providers predict which patients are at higher risk for this condition.

To participate in the study, individuals must be female, aged 20 to 70, and have been diagnosed with breast cancer between 2010 and 2020. Participants should have complete medical records, including details about their diagnosis, treatment, and any follow-up care. However, those with certain conditions, such as autoimmune diseases or other cancers, will not be eligible. Although the study is not yet recruiting participants, it will provide valuable insights that could improve care for future breast cancer patients.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients diagnosed with breast cancer by histopathology;
• • 2. Age between 20 and 70 years old;
• • 3. The first diagnosis time is between 2010 and 2020;
• • 4. Complete diagnosis and treatment information, including basic information, breast cancer diagnosis, surgery, recurrence diagnosis data (including the diagnosis of the metastasis sites), anti-tumor treatment data, bone health and bone metastasis-related diagnosis and treatment data, etc.;
• • 5. Sufficient available follow-up information.
• Exclusion Criteria:
• • 1. Missing important basic information (including initial and recurrent pathology, stage, pathological grade and time, surgery time, and drug treatment);
• • 2. With distant metastasis at the initial diagnosis;
• • 3. Patients with autoimmune diseases or aggressive viral infections (such as HIV or hepatitis);
• • 4. Other malignant tumors;
• • 5. Unclear information about distant metastasis.