Comparison of Method for Skin Closure in Colorectal Cancer.

Launched by YOON SUK LEE · Aug 8, 2024

Keywords

ClinConnect Summary

This study compares two methods doctors use to close the skin after colorectal cancer surgery: a tissue adhesive glue (skin bond) versus the traditional skin stapler. The main question is which method has a lower rate of surgical site infections within 30 days after surgery. Researchers will also look at secondary questions like how much pain people have after surgery and how the costs of wound care compare between the two methods.

To join, adults aged 19 to 80 who are having planned colorectal surgery and are generally healthy (ASA score 1–2) can be eligible. People with very high medical risk, those over 80, those having other major surgeries, or with uncontrolled diabetes are usually not eligible. Participants will be randomly assigned to receive either skin adhesive or a skin stapler and will be followed for up to about a year to assess infections, pain, recovery, and costs. The study is being done at Seoul St. Mary’s Hospital in Korea and is currently enrolling, with about 304 participants planned. Data from individual patients are not planned to be shared publicly.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • underwent elective colorectal surgery
• • aged 19 to 80 years
• • ASA (American Society of Anesthesiologists) score: 1, 2
• • surgical approach such as laparoscopic or Robotic Xi platform
• Exclusion Criteria:
• • ASA score above 3
• • Aged over 80 years
• • underwent combined surgery for other organ resection
• • uncontrolled DM