The Outcome of Injured Cervical Spinal Cord with Uncontrolled Swelling Under Duraplasty

Launched by CHANG GUNG MEMORIAL HOSPITAL · Aug 12, 2024

Keywords

ClinConnect Summary

The clinical trial titled "The Outcome of Injured Cervical Spinal Cord with Uncontrolled Swelling Under Duraplasty" is designed to explore whether a specific surgical technique called duraplasty, combined with standard surgery to relieve pressure on the spinal cord, can lead to better recovery outcomes for individuals with severe cervical spinal cord injuries. The goal is to see if this approach improves motor function—like moving arms and hands, as well as bladder and bowel control—ultimately enhancing the quality of life for patients. The trial will involve patients who are 18 years or older and have suffered a severe spinal cord injury in the neck region, provided they undergo surgery within 72 hours of the injury and can give consent.

Participants in this trial can expect to receive a well-coordinated treatment plan in a single major trauma center, where all surgeons will follow the same guidelines to ensure consistency. This helps to address some of the uncertainties surrounding the current treatment methods. By focusing on improving recovery and functioning after such serious injuries, the researchers hope to provide valuable insights that can help future patients regain control and improve their everyday lives.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years
• • Severe cervical (C2 - T1) traumatic spinal cord injury (AIS grade A-C)
• • Deemed to require and be suitable for surgery that includes laminectomy or diskectomy by local surgeon
• • Surgery within 72 hours of traumatic spinal cord injury
• • Able to provide informed consent or consultee declaration or proxy consent
• Exclusion Criteria:
• • Life-limiting or rehabilitation-restricting co-morbidities
• • Thoracic or lumbar traumatic spinal cord injury
• • Probable dural tear due to injury
• • Other central nervous system disease