Evaluation of the Effect of Central Sensitivity on Pain and Functional Status After Total Knee Joint Replacement Surgery

Launched by ISTANBUL UNIVERSITY · Aug 10, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how a condition called central sensitization affects pain and recovery after total knee joint replacement surgery in patients with knee osteoarthritis. Central sensitization means that the nervous system might be more reactive to pain signals, which can lead to more intense pain. The researchers want to see if patients with this condition experience different levels of pain and functional ability, both before and after their surgery, compared to those without central sensitization.

To participate in this study, you need to be between 60 and 75 years old and have a primary diagnosis of knee osteoarthritis, which means your knee pain is not caused by another condition. You should also be planning to have knee replacement surgery. However, if you have other health issues, such as certain uncontrolled diseases or if you’re planning a revision surgery, you won't be eligible. If you join the study, you'll be evaluated for your pain and how well you can use your knee before and after the surgery, helping researchers understand the impact of central sensitization on recovery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of primary knee osteoarthritis
• • Planning for total joint replacement surgery for the knee
• • Being between the ages of 60-75
• Exclusion Criteria:
• • Having secondary knee osteoarthritis
• • Planning for knee total joint prosthesis revision
• • Having uncontrolled systemic disease (such as diabetes mellitus, hypertension, thyroid disease)
• • Having neuromuscular disease
• • Having a body mass index over 40