Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens

Launched by CHU DE REIMS · Aug 12, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating a new method for diagnosing ventilator-associated pneumonia (VAP), which is a type of lung infection that can occur in patients who are on a ventilator in the intensive care unit (ICU). The trial aims to see if a test called multiplex PCR, which can quickly detect several types of bacteria and their drug resistance, is more effective than the standard testing currently used. This could help doctors make faster and better decisions about treatment for patients suspected of having VAP.

To be eligible for this trial, participants need to be adults who are in the ICU, have been on a ventilator for at least 48 hours, and have suspected VAP that requires a specific test called bronchoalveolar lavage (BAL). Unfortunately, patients who are pregnant, have had VAP during the same hospital stay, or are under legal protection cannot participate. If you or a loved one is eligible, the trial will involve a simple test to collect samples from the lungs, which will help researchers understand if this new testing method can improve care for patients with VAP.

Gender

ALL

Eligibility criteria

• inclusion criteria :
• • Adult patients, hospitalized in intensive care unit
• • on mechanical ventilation for at least 48 hours
• • Suspected VAP
• • With an indication for bronchoalveolar lavage (BAL)
• exclusion criteria :
• • Patients under legal protection or without social security coverage
• • Pregnant women
• • Previous episode of VAP during the same hospitalization