Post Surgical Multimodal Analgesia With Oral Strong Opioids

Launched by TRI-SERVICE GENERAL HOSPITAL · Aug 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how well oral strong opioids work for managing pain after common orthopedic surgeries, such as fixing broken bones or replacing joints. The goal is to see if using these opioids along with other pain relief methods can help reduce side effects and make patients feel better about their pain management. The trial will look at how effective this approach is in improving patient comfort and satisfaction after surgery.

To participate in this study, you must be at least 18 years old and scheduled for one of the following surgeries: fixing a broken bone, spinal fusion, or joint replacement. You also need to need pain relief methods that include oral strong opioids. If you join, you will be asked to fill out some questionnaires and share information about your medical care. If you have a history of substance abuse, are using certain types of pain medications, or have specific medical conditions, you may not be eligible to participate. The trial is not yet recruiting participants but aims to provide useful insights into pain management after orthopedic procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Aged 18 or older
• 2. Must undergo one of the following treatments:
• • (1) Fracture of upper or lower limbs or pelvis requiring internal fixation surgery (2) Spinal fusion surgery (3) Joint replacement surgery 3. Requiring multimodal analgesics for postoperative pain control, with oral strong opioids as the primary opioid analgesic, as assessed by his/her physician.
• • 4. Voluntarily sign the informed consent form and agree to the collection of clinical questionnaires and medical-related information for this study.
• Exclusion Criteria:
• • 1. Patients who have not received any or have only received oral potent opioids for no more than 1 day during the postoperative hospitalization period (including those known to be intolerant or allergic to opioid medications).
• • 2. Patients who have received or are expected to use long-acting opioid injections within 7 days before surgery or during the postoperative hospitalization period.
• • 3. Patients who use patient-controlled analgesics for pain control after surgery.
• • 4. Patients with a history of substance abuse or who require continuous treatment with other opioid receptor agonists or antagonists (such as naloxone or methadone).
• • 5. Patients with a history of mental illness who continue to require medication control from 28 days before surgery and until discharge.
• • 6. Other cases deemed ineligible by the study investigator.