Pilot Trial Investigating Every Other Day Dosing of Oral Iron in Premature Infants (IQONic)

Launched by CHRISTUS HEALTH · Aug 13, 2024

Keywords

ClinConnect Summary

The IQONic trial is studying how often premature infants should take oral iron to help with iron deficiency, which can lead to anemia (a condition where you don’t have enough healthy red blood cells). This trial will compare giving iron every day versus every other day to see if both methods help achieve similar levels of iron in the body by the time the babies reach 36 weeks of age. The goal is to find the best way to support these fragile infants in getting the nutrients they need.

To be eligible for this study, infants must be hospitalized, born prematurely between 26 to 32 weeks of gestation, and currently receiving full feedings by mouth. However, infants with certain health conditions or those who have received iron through other methods before the study cannot participate. If your baby qualifies and decides to join, they will be part of a careful observation process to help researchers understand the best practices for treating iron deficiency in premature infants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children (Minor \< 18 years of age)
• • Neonates
• • Hospitalized
• • Premature infants who are on full enteral feeds and are started on oral iron
• • Premature infants who completed 26 0/7 to 32 6/7 weeks' gestation at birth
• Exclusion Criteria:
• • • Infants with known congenital anomalies or chromosomal abnormalities (such as Trisomy 18 or Trisomy 21), conditions that affect iron metabolism (such as thalassemia or hemochromatosis), bleeding disorders or coagulopathy, and received iron parenterally prior to randomization