Clinical Application Research of Scleral Lenses in Ocular Surface Diseases

Launched by SECOND AFFILIATED HOSPITAL, SCHOOL OF MEDICINE, ZHEJIANG UNIVERSITY · Aug 13, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the use of scleral lenses to help people with irregular corneal astigmatism caused by ocular surface diseases. Irregular corneal astigmatism means that the front part of the eye has an uneven shape, which can cause blurry vision and discomfort. The researchers want to see if wearing scleral lenses can improve vision, increase comfort, and enhance overall satisfaction for patients. The study is currently recruiting participants who are at least 18 years old and have been diagnosed with conditions like post-keratoconus or corneal irregularities.

If you choose to participate, you will undergo a thorough eye examination and, if eligible, be fitted with scleral lenses. You will then return for follow-up visits at one week, one month, and three months after getting your lenses to assess how well they are working for you. Throughout the trial, your vision and comfort levels will be closely monitored, and you'll be asked to complete a questionnaire to share your experiences. This trial is important because it aims to improve the quality of life for individuals dealing with challenging eye conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with irregular corneal astigmatism, including those with post-keratoconus cross-linking surgery, post-keratoplasty, and corneal irregularities caused by trauma; Volunteers who are willing to participate in this trial, have signed the informed consent form, and are willing to cooperate with the treatment and follow-up; Individuals aged 18 years or older (including 18 years old), with no gender restrictions; Cases collected from January 2023 to August 2024.
• Exclusion Criteria:
• • Unable or unwilling to sign the consent form, or unable to follow the study procedures; Nursing or pregnant women; Individuals with acute ocular inflammation or infection; Corneal endothelium: Cell Density (CD) \<1000/mm²; Individuals required to wear lenses overnight; Poor compliance; Those who do not meet the hygiene requirements for lens wear; Individuals whom the investigator deems have other reasons making them unsuitable for the trial.