Proof-of-concept Study on Dyspnea Analysis Via GapCO2

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Aug 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a method to better understand why some patients experience sudden shortness of breath, also known as acute dyspnea. Researchers want to see if a specific measurement called GapCO2 can help determine whether the cause of this breathing difficulty is related to heart issues or not. To participate, patients must be at least 18 years old and have come to the emergency department with signs of breathing trouble, such as fast breathing or low oxygen levels. It's important that they are included in the study within one hour of their arrival.

If eligible, participants will have a blood test to measure the gases in their blood and will also be monitored using a special device that measures carbon dioxide through the skin. The overall goal of the study is to improve how doctors diagnose and treat patients with breathing problems. Since this trial is not yet recruiting, there’s no immediate action required, but it will help advance our understanding of acute dyspnea in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Patient presenting with acute dyspnea defined by a sensation of respiratory discomfort with at least one of the following criteria: RR ≥ 22 and/or SpO2 \< 95%
• • Arterial blood gas sampling performed as part of care
• • Inclusion less than 1 hour after arrival time to the emergency department
• • Non-opposition to participation in the study
• Exclusion Criteria:
• • Temperature greater than or equal to 37.5°C
• • Patient who has already received a diuretic or vasodilator treatment in the emergency department or by a prehospital medical team
• • Systolic blood pressure less than or equal to 100 mmHg and/or signs of peripheral hypoperfusion
• • Inability to express refusal to participate in the study