Effectiveness of Calcium Silicate and Sodium Fluoride Nanoparticles in The Management of Dentin Hypersensitivity

Launched by MINIA UNIVERSITY · Aug 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how effective two different types of toothpaste can be in helping people with dentin hypersensitivity, which is a condition that causes pain or discomfort in the teeth when exposed to certain triggers like hot, cold, or sweet foods. One toothpaste contains Calcium Silicate Nanoparticles (CSNPs), while the other contains Sodium Fluoride Nanoparticles. The goal is to see which toothpaste better helps to block the tiny tubes in the teeth that can cause this sensitivity.

To participate in the trial, you need to be between 20 and 40 years old and have areas on your teeth that are sensitive, particularly on the front teeth, canines, and some molars. You should be in good overall health and willing to provide written consent. However, certain conditions may disqualify you, such as having chipped teeth, dental work that could interfere with the study, or ongoing treatments that affect tooth sensitivity. If you decide to join, you can expect to use the toothpaste for a period of time and help researchers understand which option works better for managing tooth sensitivity.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Hypersensitive areas on facial surfaces of the teeth (incisors, cuspids, bicuspids, and first molars with exposed cervical dentine)
• • Areas with hard tissue erosion
• • cuneiform defect, pathological abrasion.
• • Gingival recession
• • Good overall physical health
• • Age between 20 to 40 years; and provision of written informed consent
• Exclusion Criteria:
• • chipped teeth
• • Defective restorations
• • fractured un displaced cuspids
• • deep dental caries
• • deep periodontal pockets
• • orthodontic appliances, dentures, or bridgework that would interfere with the evaluation of hypersensitivity.
• • periodontal surgery within the previous 6 months.
• • ongoing treatment with antibiotics and/or anti-inflammatory and/or analgesic drugs.
• • ongoing treatment for tooth hypersensitivity, pregnancy, or lactation; heavy smoking and alcohol or drug abuse.