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Search / Trial NCT06558201

Open Label Extension Study of NCT06221852

Launched by MCLEAN HOSPITAL · Aug 14, 2024

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

First Episode Psychosis Ketogenic Diet Keto Brain Energy Metabolism Insulin Resistance Schizoaffective Disorder Bipolar Disorder Magnetic Resonance Spectroscopy (Mrs) Redox Creatine Kinase

ClinConnect Summary

In this 12-week single arm open label extension study of NCT06221852, the investigators aim to assess the longer term efficacy, safety and tolerability of the ketogenic diet in participants completing the randomized study phase of NCT06221852. Investigators will assess longer term effects on energy metabolism, insulin resistance and psychiatric symptoms.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Participants who met original entry criteria in, and completed, the randomized 12-week study of NCT06221852.
  • Exclusion Criteria:
  • -No longer meeting original entry criteria from the randomized 12-week study of NCT06221852.

About Mclean Hospital

McLean Hospital, a leading psychiatric affiliate of Harvard Medical School, is dedicated to advancing mental health care through innovative research and clinical trials. Renowned for its commitment to scientific excellence, McLean harnesses a multidisciplinary approach to address a wide range of psychiatric disorders, including depression, anxiety, and schizophrenia. With state-of-the-art facilities and a team of expert clinicians and researchers, the hospital aims to develop effective treatment strategies and improve patient outcomes. Its robust clinical trial program fosters collaboration and contributes to the broader understanding of mental health, ultimately enhancing therapeutic options for individuals in need.

Locations

Belmont, Massachusetts, United States

Patients applied

0 patients applied

Trial Officials

Virginie-Anne Chouinard, MD

Principal Investigator

Mclean Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported