Incisional Negative Pressure Therapy to Prevent Animal Induced Wound Infection

Launched by PEKING UNIVERSITY FIRST HOSPITAL · Aug 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment method called incisional negative pressure wound therapy (iNPWT) to see if it can help prevent infections in deep wounds caused by animal bites or scratches. Each year, millions of people are hurt by animals, which can lead to serious infections. In this study, researchers will compare iNPWT, which uses a gentle suction to help wounds heal and stay clean, with regular gauze dressings on patients who have had severe animal injuries. The goal is to find out if iNPWT can lower the chances of infection and speed up healing for these types of wounds.

To participate in this study, you would need to have a deep wound from an animal bite that requires stitches and is at least 2 centimeters long. The study is open to all adults aged 18 and older who meet these criteria. Unfortunately, if you've had an infection in your wound or waited more than 8 hours to get treated, you wouldn't be eligible to join. Participants will receive either the iNPWT treatment or standard gauze and will be monitored to see how well their wounds heal and if there are any infections. This trial aims to provide valuable information that could improve how we treat animal bite wounds in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Limds injuries caused by animals, first or second animal injury to Grade III exposed patients, with deep wounds reaching the fat layer, tendons, and even penetrating injuries.
• • Patients with wounds\>2cm and severe injuries that even require surgical treatment.
• Exclusion Criteria:
• • Missing or incomplete follow-up data within 30 days.
• • Patients who have been infected with wounds or have been injured for more than 8 hours before seeking medical attention.
• • Acupuncture like wound (\<2mm).
• • Patients with whole skin detachment.