Exergame and Robotic Therapy Impact on Tenascin-C and Functional Outcome on Stroke Patients

Launched by HASANUDDIN UNIVERSITY · Aug 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different types of therapy can help improve hand function in patients who have had a stroke. Specifically, it will compare three approaches: robotic therapy, exergame therapy (which uses video games to encourage movement), and standard rehabilitation therapy. The goal is to see which method is most effective in helping patients recover their abilities over time and to understand how these therapies might affect a specific protein in the body called Tenascin-C, which is linked to healing.

To be eligible for this trial, participants need to have experienced a stroke and be in stable health, meaning their vital signs and neurological condition are steady. They must also be able to understand the consent process and watch television from about one meter away. However, those with certain conditions, like severe cognitive disorders or uncontrolled medical issues, may not qualify. If chosen to participate, individuals will engage in therapy sessions and be monitored regularly to evaluate their progress. This study is currently looking for participants of all ages and genders who meet the criteria.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients after ischemic or hemorrhagic stroke
• • stable hemodynamics and neurologic state.
• • Patients have never undergone treatment with any intervention
• • Able to watch television with or without glasses from a distance of 1 meter.
• • Patients can understand informed consent to participate in research
• Exclusion Criteria:
• • Patients with a history of seizures or epilepsy.
• • Patients with severe cognitive disorders that can interfere with research objectives (MMSE score \<24).
• • Patients with field deficits or severe vision disorders.
• • The patient is unable to sit upright without help.
• • Patients with significant pain in the affected upper limb.
• • Patients with significant sensory decreases in the upper limb that are affected
• • Patients with other medical conditions (musculoskeletal, neuromuscular, cardio respiration) are uncontrolled and are at risk of disrupting the ability to exercise.
• • Dropout Criteria
• • Patients who were declared dead
• • Refusing to continue the training session or less \< 50% of all sessions.
• • Experiencing hemodynamic and neurological disorders during the training program process.
• • Experiencing cybersickness twice in successive training sessions