Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy

Launched by MEDICAL UNIVERSITY OF WARSAW · Aug 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether giving magnesium sulfate through an IV (intravenously) can help reduce the need for opioid painkillers in children undergoing laparoscopic appendectomy, which is a minimally invasive surgery to remove the appendix. Researchers believe that magnesium sulfate may help manage pain and lessen the body's stress response during surgery, but there hasn't been enough research in children to confirm this yet.

To be eligible for the study, children between the ages of 5 and 17 who are in stable health and scheduled for an emergency appendectomy may participate. However, children with certain health issues, such as allergies to magnesium sulfate, kidney problems, or those taking specific medications, cannot join. Participants in the trial will receive magnesium sulfate during their surgery and will be monitored to see how it affects their pain management and overall recovery. This study is important because it could help improve pain management options for children undergoing surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ASA (American Society of Anesthesiologists) physical status class 1E, 2E, 3E (E - emergency)
• • Patients undergoing laparoscopic appendectomy
• Exclusion Criteria:
• • Allergy to the magnesium sulfate or the excipient
• • Hypermagnesemia
• • Renal failure (GFR \<30 ml/min)
• • Myasthenia gravis
• • Preoperative atrioventricular block
• • Hypotension
• • The use of digitalis glycosides
• • The use of oral anticoagulants
• • ASA physical status class 4E or higher
• • Chronic treatment with analgesics
• • Legal guardians or patient refusal