Combined Rehabilitation and Nutritional Support vs. Standard Care in In-Hospital Endocarditis Treatment

Launched by JOHANNES GRAND · Aug 19, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at the effects of a combined rehabilitation and nutritional support program compared to standard care for patients being treated for infective endocarditis (IE), a serious infection of the heart. The goal is to see if this specialized program can help improve patients' physical health, strength, and overall quality of life during their hospital stay. Patients with IE often face long hospitalizations that can lead to weakness and other health issues, so finding ways to support them better is very important.

To participate in this trial, individuals must be at least 18 years old and diagnosed with a specific type of bacterial infective endocarditis that requires intravenous (IV) antibiotics. However, those who are unstable in their condition, expected to leave the hospital within three days, or have certain health issues like severe immune problems or fungal infections will not be eligible. Participants can expect to receive additional support through physical therapy and nutritional help during their treatment, which may lead to better health outcomes. This trial is currently recruiting participants, and it's a great opportunity for those who qualify to contribute to important research that could improve care for future patients.

Gender

ALL

Eligibility criteria

• • INCLUSION CRITERIA
• • Clinical diagnosis of left-sided (native, prosthetic, or culture-negative) bacterial infective endocarditis mandating iv antibiotic treatment, including Cardiac Implantable Electronic Devices infections, irrespective of cause and location as defined by the ESC modified Duke Criteria
• • Age ≥ 18 years
• • EXCLUSION CRITERIA
• • Hemodynamic instability (defined as a systolic blood pressure \<90 mmHg and lactate \>2.2 mmol/l measured in an arterial blood gas.
• • Expected to be discharged within 3 days
• • Immunocompromised due to severe combined immunodeficiency, HIV, or hematological malignancy
• • Fungal endocarditis
• • Pregnancy
• • Unwilling or unable to sign or understand informed consent