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Search / Trial NCT06567483

A Comparison of Protein-bound and Large Molecular Weight Uremic Toxin Removals With Novel Super High-flux Dialyzer Between Hemodialysis and High Volume Online HDF Modalities

Launched by CHULALONGKORN UNIVERSITY · Aug 21, 2024

Trial Information

Current as of May 06, 2025

Completed

Keywords

Super High Flux Dialyzers Medium Cut Off Membrane Protein Bound Uremic Toxin Indoxyl Sulfate Dialysate Albumin Loss Albumin Kappa Free Light Chain Lambda Free Light Chain Pre Dilution Online Hdf Conventional Hemodialysis

ClinConnect Summary

Other secondary outcomes that the researcher wants to study are

1. The reduction ratio of Beta2microglobulin, kappa and lambda free light chain
2. Serum albumin and dialysate albumin loss
3. Quality of life, muscle mass and nutritional status of the patients

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Chronic hemodialysis patients in King Chulalongkorn Memorial hospital
  • Residual renal function less than 100 ml/day
  • Exclusion Criteria:
  • Dialyzer allergy
  • Malnutrition requiring intradialytic parenteral nutrition
  • Cirrhosis child C or decompensated cirrhosis
  • Active uncontrolled infection
  • Active cardiovascular disease
  • Advanced stage malignancy
  • Predicted to be undergone living related kidney transplant within 1 year

About Chulalongkorn University

Chulalongkorn University, one of Thailand's premier academic institutions, is dedicated to advancing medical research and enhancing healthcare outcomes through innovative clinical trials. With a strong emphasis on collaboration and interdisciplinary approaches, the university leverages its extensive resources and expertise in various medical fields to conduct rigorous scientific investigations. Chulalongkorn University aims to contribute to global health advancements by fostering a culture of excellence in research, education, and community service, ultimately improving patient care and public health standards.

Locations

Pathum Wan, Bangkok, Thailand

Patients applied

0 patients applied

Trial Officials

Rossanun Shoosanglertwijit

Principal Investigator

Chulalongkorn University

Khajohn Tiranathanagul

Principal Investigator

Chulalongkorn University

Pajaree Chariyavilaskul

Principal Investigator

Chulalongkorn University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported