Bacterial Reduction After Supplementary Disinfection Procedures in Infected Root Canals

Launched by ABHISHEK PAROLIA · Aug 22, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to find out how effective three different types of root canal procedures are in reducing bacteria in infected teeth. The main condition being studied is called dental pulp necrosis, which happens when the tissue inside a tooth dies and can lead to pain and infection. The study is currently recruiting participants who are 18 years or older and have a specific type of tooth infection that has been confirmed by tests and imaging.

To be eligible for this trial, participants must have a tooth that has no response to cold or electric tests, meaning the nerve inside is not alive. However, certain conditions would exclude someone from participating, such as having a tooth that is still alive, having a severe infection, or being pregnant. If you join the study, you will receive one of the three root canal treatments being tested, and the goal is to see how well each method works to reduce bacteria and improve dental health. This trial aims to help improve future treatments for root canal infections.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of pulp necrosis with apical periodontitis (AP) confirmed by pulp tests, clinical and radiographic evidence.
• • Tooth with no response to cold and electric pulp testing (done at screening).
• • Single canalled premolars with intact pulp chamber walls.
• • Patient must be 18 years of age or older
• Exclusion Criteria:
• • Teeth with vital pulp.
• • Teeth with incomplete root formation (immature with apical periodontitis).
• • Teeth with extensive crown destruction.
• • Teeth with previous endodontic treatment or intervention (pulp debridement).
• • Teeth with acute/ chronic apical abscess.
• • Teeth with internal or external resorption.
• • Teeth with non-odontogenic facial pain.
• • Teeth with periodontal pockets deeper than 4 mm.
• • Teeth with advanced untreated periodontal disease or recent periodontal surgery.
• • Teeth with mobility score greater than 2.
• • Teeth with a fracture or visible crack.
• • Patients with diabetes or immune compromised conditions.
• • Patients who received systemic antibiotics within the last 3 months.
• • Patients taking corticosteroids.
• • Patients who are pregnant.