Comparison of Compounded Topical Anesthetics

Launched by DARTMOUTH-HITCHCOCK MEDICAL CENTER · Aug 23, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how effective a specially compounded topical anesthetic, called BLT (which contains benzocaine, lidocaine, and tetracaine), is compared to a standard 4% lidocaine cream in relieving pain during certain dermatological procedures like Intense Pulse Light (IPL), Pulse Dye Laser (PDL), and microneedling. The goal is to find out which option works better to help patients feel more comfortable during these treatments.

To be eligible to participate, you need to be between 18 and 75 years old and have a scheduled appointment for one of the procedures mentioned above. However, if you have a history of allergies to any of the anesthetics being tested, certain medical conditions like heart or respiratory issues, or if you are pregnant or breastfeeding, you won't be able to join the study. If you participate, you can expect to apply either the BLT or the 4% lidocaine cream before your procedure and then share your experience regarding pain relief. This trial is currently looking for participants, so it could be a good opportunity if you are interested in helping improve pain management options for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Men and women over 18, but not more than 75 years of age.
• • Patients who have a regularly scheduled dermatology appointment for Intense Pulse Light (IPL), Pulse Dye Laser (PDL), or microneedling.
• Exclusion Criteria:
• • Any subject who has a previous history of allergy, sensitivity, and contraindication to benzocaine, lidocaine, or tetracaine.
• • Patients with cardiac/respiratory disease, seizure disorder, or neuropathies.
• • Patients who are under treatment for a dermatologic condition that may interfere with the evaluation of the study.
• • Pregnant women and women who are breastfeeding.
• • Patients who report concurrent use of anxiolytics or opiates, which may interfere with the interpretation of results.