Evaluation of iPRF With Vit.D As an Adjunct to Non-Surgical Therapy in the Treatment of Stage III Periodontitis

Launched by CAIRO UNIVERSITY · Aug 22, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to explore how effective a treatment called injectable platelet-rich fibrin (iPRF), combined with vitamin D, is for patients with Stage III periodontitis, which is a serious gum disease that affects the pockets around the teeth. The goal is to see if this combination can help improve the health of the periodontal pockets, which are the spaces between the gums and teeth where infection can occur.

To participate in this study, you need to be an adult over 18 years old, in generally good health, and diagnosed with Stage III periodontitis. Unfortunately, if you have certain dental work done recently, are a smoker, or are on certain medications, you may not be eligible. If you do qualify and choose to take part, you can expect to receive the treatment and then be followed up for three months to monitor your progress. This trial is not currently recruiting participants, but it represents a promising step toward finding better treatments for gum disease.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with healthy systemic condition.
• • 2. Adult patients ˃ 18 years old.
• • 3. Patients with Stage III periodontitis.
• • 4. Patients accept 3-month follow-up period (cooperative patients).
• • 5. Patients provide an informed consent.
• Exclusion Criteria:
• • 1. Presence of prosthetic crowns.
• • 2. Extensive interproximal restorations.
• • 3. Periodontal therapy within the last 12 months.
• • 4. Having undergone surgical periodontal therapy or undergoing orthodontic treatment.
• • 5. Ongoing drug therapy that might have an impact on the clinical signs and symptoms of periodontitis.
• • 6. The use of antibiotics or anti-inflammatory drugs 3-month prior to the procedure and till the end of 6-month of follow-up.
• • 7. Smokers.
• • 8. Pregnant females.