Neurophysiological Changes After Perturbation-based Training in Older Adults
Launched by THE HONG KONG POLYTECHNIC UNIVERSITY · Aug 23, 2024
Trial Information
Current as of July 24, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how a special type of training called perturbation-based training (PBT) can help improve balance in older adults. The researchers want to see if this training leads to changes in the brain that can help prevent falls, which is important for maintaining independence as we age. Participants will be randomly assigned to either the PBT group or a control group that receives a different type of training, and the study is currently recruiting people who meet certain criteria.
To be eligible for the trial, participants need to be at least 60 years old, live in the community, and be right-handed. They should also be able to communicate in Cantonese or Mandarin and walk independently for at least 30 minutes. Importantly, participants should not have any serious health issues, such as recent surgeries or conditions affecting their movement or balance. Throughout the trial, participants can expect to engage in training sessions and contribute to valuable research that could lead to better balance and fall prevention strategies for older adults.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Aged ≥ 60 years old
- • Community-dwelling
- • Right-handed
- • Able to communicate effectively in Cantonese or Mandarin
- • Able to walk independently on level ground for ≥ 30 minutes
- • Abbreviated Mental Test (Hong Kong version) score ≥ 6
- Exclusion Criteria:
- • Metal implants (e.g. pacemaker, artificial cochlea)
- • Uncorrected vision or hearing impairment
- • Osteoporosis
- • Hip or knee replacement within the last year
- • Musculoskeletal, cardiovascular, mental, or neurological disorders (such as Parkinson's disease) which can affect MRI examination, balance control, or exercise participation.
About The Hong Kong Polytechnic University
The Hong Kong Polytechnic University (PolyU) is a leading institution in applied research and education, dedicated to advancing knowledge and innovation in various fields, including health sciences. As a clinical trial sponsor, PolyU focuses on conducting rigorous and ethically sound research to enhance understanding of medical interventions and improve patient outcomes. The university leverages its multidisciplinary expertise, state-of-the-art facilities, and collaboration with industry partners to facilitate groundbreaking studies that address pressing health challenges. Committed to fostering an environment of academic excellence, PolyU aims to translate research findings into practical solutions that benefit society and contribute to the global advancement of healthcare.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Hong Kong, , Hong Kong
Hong Kong, , Hong Kong
Patients applied
Trial Officials
Sau Lan Tsang, PhD
Principal Investigator
The Hong Kong Polytechnic University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported