Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery
Launched by THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER, HOUSTON · Aug 23, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effects of a treatment called Photobiomodulation (PBM) on pain and healing after a specific dental surgery known as endodontic microsurgery. The goal is to see if PBM can help reduce pain after surgery and improve the healing of the surgical site, particularly the area where a small incision is made in the gum tissue.
To participate in this study, you must be between the ages of 65 and 74, and you should be in good health according to the American Society of Anesthesiologists (ASA) classification. This means you should have no serious health issues that could complicate healing, and you should not be a heavy smoker or have uncontrolled diabetes. If you qualify and decide to join, you can expect to receive the PBM treatment after your surgery, and researchers will monitor your pain levels and how well your incision heals. This study is currently looking for volunteers, and your participation could help improve future dental care for others.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • American Society of Anesthesiologists (ASA) I or II.
- • At least one tooth will receive EMS.
- • Flap design that includes at least one VRI (triangular, rectangular, papilla base or submarginal rectangular).
- Exclusion Criteria:
- • ASA III or IV.
- • Current heavy smokers (\>10 cigarettes/day)
- • Uncontrolled diabetes (HbA1c ≥ 7%) or other uncontrolled systemic diseases that may comprise healing, such as vitamin C deficiency, neutrophil deficiencies, immunodeficiency syndromes, or leukemia.
- • Surgical access on the palatal surface.
- • Acute swelling or abscess present on the day of the surgery.
- • Any event or condition that would make continued participation in the study not in the best interest of the subject, as determined by the investigator.
- • Pregnancy.
- • Development of any medical condition that might affect the treatment and clinical outcomes, as determined by the investigator.
- • Initiation of any treatment or exposure that might affect therapy's healing, as determined by the investigator.
About The University Of Texas Health Science Center, Houston
The University of Texas Health Science Center at Houston (UTHealth) is a leading academic institution dedicated to advancing health through education, research, and clinical practice. As a prominent sponsor of clinical trials, UTHealth leverages its extensive resources and expertise in biomedical research to facilitate innovative studies aimed at improving patient outcomes. The institution is committed to fostering a collaborative environment that promotes scientific discovery and the translation of research findings into effective healthcare solutions, all while adhering to the highest ethical standards and regulatory guidelines. With a multidisciplinary approach, UTHealth plays a critical role in addressing complex health challenges and enhancing the quality of life in diverse communities.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Houston, Texas, United States
Patients applied
Trial Officials
Juliana Barros, DDS,MS
Principal Investigator
The University of Texas Health Science Center, Houston
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported