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Search / Trial NCT06576622

PERIodontal Disease, Microbiota and Miscarriage

Launched by UNIVERSITY HOSPITAL, TOULOUSE · Aug 26, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Repeated Miscarriages Porphyromonas Gingivalis Saliva Biological Samples Subgingival Plaque

ClinConnect Summary

This clinical trial is exploring the relationship between gum disease (called periodontal disease), the bacteria in the mouth, and the occurrence of repeated miscarriages in women. The study specifically targets women who have experienced three or more miscarriages. During the trial, participants will undergo a routine dental check-up where their oral health will be assessed, and samples of saliva and plaque from their gums will be collected to analyze the bacteria present.

To be eligible for this study, women must have had repeated miscarriages and have at least six natural teeth. However, women who have taken antibiotics, prebiotics, or probiotics within the last month, or those with certain health risks, such as HIV, cannot participate. If you join the study, you can expect a thorough dental examination and the collection of samples as part of your regular oral health check. This research aims to better understand how oral health may impact pregnancy outcomes, which could lead to improved care for women facing similar challenges.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • women whom had repeated miscarriages
  • at least 6 natural teeth
  • Exclusion Criteria:
  • under antibiotic prebiotic or probiotics treatment one month prior to the study
  • with high infection risk (HIV,...)

About University Hospital, Toulouse

The University Hospital of Toulouse is a leading academic medical center dedicated to advancing healthcare through innovative research and clinical trials. With a strong emphasis on patient-centered care, the hospital integrates cutting-edge scientific inquiry with comprehensive clinical services. Its multidisciplinary team of healthcare professionals collaborates with renowned researchers to facilitate pioneering studies across various medical fields, aiming to enhance treatment options and improve patient outcomes. As a prominent institution in the region, the University Hospital of Toulouse is committed to fostering an environment of excellence in both education and research within the healthcare community.

Locations

Toulouse, , France

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported